Anti-FAM58A/FITC

Quantity size:

100ul

Concentration:

1mg/ml  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

FAM58A (family with sequence similarity 58, member A) and FAM58B (family with sequence similarity 58, member B) are 248 amino acid and 252 amino acid proteins, respectively, that belong to the cyclin-like FAM58 subfamily. Existing as multiple alternatively spliced isoforms, FAM58A interacts with Sall1 and is thought to play a role in cellular proliferation. Defects in the gene encoding FAM58A are associated with toe syndactyly, telecanthus, and anogenital and renal malformations (STAR syndrome), which is characterized by renal and anogenital malformations. FAM58B, a protein that is related to FAM58A, is expressed in healthy retina and breast tissue, as well as in retinoblastoma and breast cancer cell lines, suggesting a role for FAM58B in tumor transformation and metastasis.

Also known as:

Cyclin-M; Cyclin-related protein FAM58A; FA58A_HUMAN; Fam58a; Family with sequence similarity 58 member A; STAR.

Specificity:

Rabbit Polyclonal IgG, affinity purified by Protein A.

Reacts with: Human, Mouse, Rat, Rabbit, .

Immunogen: KLH conjugated synthetic peptide derived from human FAM58A.

Predicted Molecular Weight: 28kDa.

Storage:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Application:

ICC=1:50-200  IF=1:50-200  
Excitation spectrum: 495nm
Emission spectrum: 519nm
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.

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