Retinoic acid induced 17 Polyclonal Antibody

Host: Rabbit   Reactivity:Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep,

BackGround:

Increases ligand-dependent transcriptional activity of ARand promotes AR sumoylation. The stimulation of AR activityis dependent upon sumoylation.Tissue specificity:Expressed most abundantly in ovaryand, at lower levels, in prostate, spleen and testis. Weakexpression, if any, in thymus, small intestine, colon andperipheral blood leukocytes.

Product:

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and50% Glycerol.

Molecular Weight:

115kDa

Swiss-Prot:

Q9ULJ6

Purification&Purity:

affinity purified by Protein A

Applications:

IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test

Storage&Stability:

Store at 4°C short term. Aliquot and store at -20°C longterm. Avoid freeze-thaw cycles.

Specificity:

Retinoic acid induced 17 Polyclonal Antibody detectsendogenous levels of Retinoic acid induced 17 protein.

DATA:

Note:

For research use only, not for use in diagnostic procedure.

LRRC48 is a 523 amino acid protein that contains fiveLRR (leucine-rich) repeats and one LRRCT domain. Existingas two alternatively spliced isoforms, LRRC48 isencoded by human chromosome 17p11.2.

In the process of endocytosis, essential rate-limiting regulatorof a fast recycling pathway back to the plasmamembrane. During cytokinesis, required for the postfurrowingterminal steps, namely for intercellular bridge stabilityand abscission, possibly by controlling phosphatidylinositol4,5-bis phosphate (PIP2) and SEPT2 localizationat the intercellular bridge.