JAK1 polyclonal antibody

Host: Rabbit   Reactivity:Human,Mouse,Rat

BackGround:

Members of the Janus family of tyrosine kinases (Jak1,Jak2, Jak3, and Tyk2) are activated by ligands binding toa number of associated cytokine receptors. Upon cytokinereceptor activation, Jak proteins become autophosphorylatedand phosphorylate their associated receptors to providemultiple binding sites for signaling proteins. Theseassociated signaling proteins, such as Stats, Shc, insulinreceptor substrates, and focal adhesion kinase (FAK),typically contain SH2 or other phospho-tyrosine-bindingdomains.

Product:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide,50% glycerol, pH7.2

Molecular Weight:

~ 125 kDa

Swiss-Prot:

P23458

Purification&Purity:

The antibody was affinity-purified from rabbit antiserumby affinity-chromatography using epitope-specific immunogenand the purity is > 95% (by SDS-PAGE).

Applications:

WB: 1:500~1:1000

IF: 1:50~1:200

IHC: 1:50~1:200

Storage&Stability:

Store at 4°C short term. Aliquot and store at -20°C longterm. Avoid freeze-thaw cycles.

Specificity:

JAK1 polyclonal antibody detects endogenous levels ofJAK1 protein.

DATA:

Note:

For research use only, not for use in diagnostic procedure.