RPS27 polyclonal antibody
Host: Rabbit Reactivity:Human,Rat
BackGround:
Ribosomes, the organelles that catalyze protein synthesis,consist of a small 40S subunit and a large 60S subunit.Together these subunits are composed of 4 RNA speciesand approximately 80 structurally distinct proteins. Thisgene encodes a ribosomal protein that is a component ofthe 40S subunit. The protein belongs to the S27E familyof ribosomal proteins. It contains a C4-type zinc fingerdomain that can bind to zinc. The encoded protein hasbeen shown to be able to bind to nucleic acid. It is locatedin the cytoplasm as a ribosomal component, but it has alsobeen detected in the nucleus. Studies in rat indicatethat ribosomal protein S27 is located near ribosomal proteinS18 in the 40S subunit and is covalently linked totranslation initiation factor eIF3. As is typical for genesencoding ribosomal proteins, there are multiple processedpseudogenes of this gene dispersed through the genome.
Product:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide,50% glycerol, pH7.2
Molecular Weight:
~ 9kDa
Swiss-Prot:
P42677
Purification&Purity:
The antibody was affinity-purified from rabbit antiserumby affinity-chromatography using epitope-specific immunogenand the purity is > 95% (by SDS-PAGE).
Applications:
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Storage&Stability:
Store at 4°C short term. Aliquot and store at -20°C longterm. Avoid freeze-thaw cycles.
Specificity:
RPS27 polyclonal antibody detects endogenous levels ofRPS27 protein.
DATA:
Note:
For research use only, not for use in diagnostic procedure.