RRBP1 polyclonal antibody

Host: Rabbit   Reactivity:Human,Mouse

BackGround:

This gene encodes a ribosome-binding protein of the endoplasmicreticulum (ER) membrane. Studies suggestthat this gene plays a role in ER proliferation, secretorypathways and secretory cell differentiation, and mediationof ER-microtubule interactions. Alternative splicing hasbeen observed and protein isoforms are characterized byregions of N-terminal decapeptide and C-terminal heptadrepeats. Splicing of the tandem repeats results in variationsin ribosome-binding affinity and secretory function.The full-length nature of variants which differ in repeatlength has not been determined. Pseudogenes of this genehave been identified on chromosomes 3 and 7, andRRBP1 has been excluded as a candidate gene in thecause of Alagille syndrome, the result of a mutation in anearby gene on chromosome 20p12.

Product:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide,50% glycerol, pH7.2

Molecular Weight:

~ 120 kDa

Swiss-Prot:

Q9P2E9

Purification&Purity:

The antibody was affinity-purified from rabbit antiserumby affinity-chromatography using epitope-specific immunogenand the purity is > 95% (by SDS-PAGE).

Applications:

WB 1:500 - 1:2000

Storage&Stability:

Store at 4°C short term. Aliquot and store at -20°C longterm. Avoid freeze-thaw cycles.

Specificity:

RRBP1 polyclonal antibody detects endogenous levels ofRRBP1 protein.

DATA:

Note:

For research use only, not for use in diagnostic procedure.