APOL3 polyclonal antibody

Host: Rabbit  Reactivity: Human,Mouse,Rat

BackGround:Apolipoproteins are protein components of plasma lipoproteins.The apolipoprotein L gene family encodes sixhighly homologous proteins designated apoL1-6, whichare associated with large high density type lipoproteins(HDL). The human apoL family maps to chromosome22q12.1-13.1 within a 127,000 bp region. apoL2 andapoL3 may allow the binding of lipids to organelles ormay be involved in the movement of lipids in the cytoplasm.apoL2 localizes to the cytoplasm and is widelyexpressed, with the highest levels observed in the lung,thymus, pancreas, placenta, adult brain and prostate. TheapoL2 protein is also detected in the spleen, liver, kidney,colon, small intestine, uterus, spinal cord, adrenal gland,salivary gland, trachea, mammary gland, skeletal muscle,testis and fetal brain and liver. apoL3 also localizes to thecytoplasm and is widely expressed, with highest levelsdetected in the prostate, lung and placenta. It is also detectedin kidney, bone marrow, spleen, thymus, spinalcord, adrenal gland, salivary gland, trachea and mammarygland. Lower levels of apoL3 are observed in the brain,heart, fetal liver, pancreas and testis.

Product:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide,50% glycerol, pH7.2

Molecular Weight:

~ 36, 44kDa

Swiss-Prot:

O95236

Purification&Purity:

The antibody was affinity-purified from rabbit antiserumby affinity-chromatography using epitope-specific immunogenand the purity is > 95% (by SDS-PAGE).

Applications:

WB: 1:500~1:1000

Storage&Stability:

Store at 4°C short term. Aliquot and store at -20°C longterm. Avoid freeze-thaw cycles.

Specificity:

APOL3 polyclonal antibody detects endogenous levels ofAPOL3 protein.

DATA:

Note:

For research use only, not for use in diagnostic procedure.